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Documented to be the best non-surgical option for prevention and healing of anal fissures. Whether you have a hemorrhoid or a fissure, your doctor will probably try conservative treatment options, including at-home care, first. Because the two conditions cause similar discomforts, similar treatments will relieve symptoms. Botulinum toxin is a relatively new treatment for anal fissures. Botulinum toxin is a powerful poison thats safe to use in small doses. If you have an anal fissure, an injection of the toxin can be used to paralyse your sphincter muscle. soak in a sitz bath with warm water for twenty minutes, once a day, or as needed. Wipes many people suffer from hemorrhoids and anal fissures and they often turn to the use of special wipes to alleviate the pain. Treating anal fissures at least 50 percent of fissures heal by themselves and can be treated with home remedies including application of special medicated cream, use of stool softeners, avoidance of constipation, or sitz baths (soaking the area in plain warm water for 10-20 minutes, several times a day). Sitz baths, or hip baths, can promote healing of an anal fissure. By soaking the rectal area in a tub of warm water -- two or three times a day for 10 to 15 minutes -- you can clean the anus,. Documented to be the best non-surgical option for prevention and healing of anal fissures.