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An anal yeast infection often causes intense and persistent anal itching, also called pruritus ani. People can treat anal yeast infections with over-the-counter (otc) antifungals or prescription. Examples of possible causes of anal itching include hemorrhoids, anal fissures, pinworms (enterobius vermicularis), spicy foods, and medications. Additional symptoms associated with anal itching include burning and pain if the anal skin is traumatized by scratching. The diagnosis of the cause of pruritis ani requires examination of the anus for. Diflucan fluconazole itch itching a 36-year-old female asked vaginal itch, clumpy white discharge, no odor. an anal yeast infection is often characterized by persistent and intense anal itching. Hello, welcome to hcm, as you are on diflucan for five days and most of your symptoms have comedown. The itching in the anus may be due to many reasons starting from food to parasitic infections. Its been 3 days, still itching and having white discharge, but less. I have had intense vaginal itching for a couple of weeks now. I went to my gyno and she said i definitely had a yeast infection and gave me 2 diflucan. To randrews8902 from bestpup sounds to me like the monistat cream and the diflucan have done their job and stopped the infectionitching. I would apply a little vaseline to help in the aid of the blisters.